beta-Carotene from foods, not from supplements, reduced the risk of death from cancer, stroke, diabetes and cardiovascular diseases.
The studies researchers speculate that beta-Carotene may play a role in the modification/prevention of LDL oxidation and lipid peroxidation, consequently lowering CVD risk and mortality.
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.313409